LYMPHOID NEOPLASIA Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma
نویسندگان
چکیده
1Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL; 2Center for Cancer Systems Biology, School of Medicine, Stanford University, Stanford, CA; 3Weill Cornell Medical College, New York, NY; 4Department of Pathology, Stanford University School of Medicine, Stanford, CA; 5Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain; 6Consultoria em Patologia, Botucatu, Brazil; and 7Division of Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain
منابع مشابه
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma.
LMO2 regulates gene expression by facilitating the formation of multipartite DNA-binding complexes. In B cells, LMO2 is specifically up-regulated in the germinal center (GC) and is expressed in GC-derived non-Hodgkin lymphomas. LMO2 is one of the most powerful prognostic indicators in diffuse large B-cell (DLBCL) patients. However, its function in GC B cells and DLBCL is currently unknown. In t...
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